Query: NC_014921:313312 Mycoplasma fermentans M64 chromosome, complete genome Lineage: Mycoplasma fermentans; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Mycoplasma fermentans has been isolated from the respiratory and urogenital tract, primarily from immunocompromised patients and may be a factor in the progression of HIV infection to AIDS. In addition this organism can be detected in the blood and joints of patients with rheumatoid arthritis.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.