Query: NC_014914:1678973 Taylorella equigenitalis MCE9 chromosome, complete genome
Lineage: Taylorella equigenitalis; Taylorella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This strain was isolated in 2005 from the urethral fossa of a 4-year-old stallion from a stud farm in the Haute-Savoie, France. This species is a microaerophilic Gram-negative coccobacillus, classified in the Alcaligenaceae family. It is the causative agent of the contagious equine metritis (CEM), a sexually-transmitted infection of horses first reported in 1977, and actually detected in many countries and in various breeds of horses. CEM is characterized in infected mares by abundant mucopurulent vaginal discharge and a variable degree of vaginitis, endometritis and cervicitis that usually result in temporary infertility, whereas no clinical signs have been observed in stallions.
Subject: NC_010742:1595065 Brucella abortus S19 chromosome 1, complete sequence
Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.