Query: NC_014914:1092546 Taylorella equigenitalis MCE9 chromosome, complete genome Lineage: Taylorella equigenitalis; Taylorella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This strain was isolated in 2005 from the urethral fossa of a 4-year-old stallion from a stud farm in the Haute-Savoie, France. This species is a microaerophilic Gram-negative coccobacillus, classified in the Alcaligenaceae family. It is the causative agent of the contagious equine metritis (CEM), a sexually-transmitted infection of horses first reported in 1977, and actually detected in many countries and in various breeds of horses. CEM is characterized in infected mares by abundant mucopurulent vaginal discharge and a variable degree of vaginitis, endometritis and cervicitis that usually result in temporary infertility, whereas no clinical signs have been observed in stallions.
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General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.