Query: NC_014914:1092546 Taylorella equigenitalis MCE9 chromosome, complete genome
Lineage: Taylorella equigenitalis; Taylorella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This strain was isolated in 2005 from the urethral fossa of a 4-year-old stallion from a stud farm in the Haute-Savoie, France. This species is a microaerophilic Gram-negative coccobacillus, classified in the Alcaligenaceae family. It is the causative agent of the contagious equine metritis (CEM), a sexually-transmitted infection of horses first reported in 1977, and actually detected in many countries and in various breeds of horses. CEM is characterized in infected mares by abundant mucopurulent vaginal discharge and a variable degree of vaginitis, endometritis and cervicitis that usually result in temporary infertility, whereas no clinical signs have been observed in stallions.
Subject: NC_006570:24636 Francisella tularensis subsp. tularensis Schu 4, complete genome
Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.