Pre_GI: SWBIT SVG BLASTP

Query: NC_014844:659829 Desulfovibrio aespoeensis Aspo-2 chromosome, complete genome

Lineage: Desulfovibrio aespoeensis; Desulfovibrio; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: Country: Sweden; Environment: Animal intestinal microflora, Fresh water; Isolation: Granitic rock aquifer at 600 m depth; Temp: Mesophile; Temp: 30C. Desulfovibrio aespoeensis Aspo-2 is a halotolerant, sulfate-reducing Gram-negative bacterium isolated from granitic groundwater sampled at a depth of 600 m at Aspo hard rock laboratory, Sweden.

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BLASTP Alignment.txt

Subject: NC_004557:558500 Clostridium tetani E88, complete genome

Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.