Query: NC_014814:3926676 Mycobacterium sp. Spyr1 chromosome, complete genome Lineage: Mycobacterium gilvum Spyr1; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Country: Greece; Environment: Creosote-contaminated soil, Soil; Temp: Mesophile; Isolation: creosote contaminated soil; Country:Greece: near Ioannina, Epirus. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. These organism are common in soil and freshwater.
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General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.