Pre_GI: SWBIT SVG BLASTP

Query: NC_014802:441000 Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, complete

Lineage: Campylobacter jejuni; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Gram-negative, microaerophilic, flagellate, spiral bacterium, Campylobacter species are the leading cause of food-borne gastroenteritis in developed countries. Infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome (GBS). Strain ICDCCJ07001 was isolated following a GBS outbreak in Shuangyang, a town in northern China in 2007, from a severely affected 15 year-old girl GBS patient who had been on a ventilator for 180 days. Her clinical symptoms were motor axonal neuropathy. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.

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BLASTP Alignment.txt

Subject: NC_012039:412837 Campylobacter lari RM2100, complete genome

Lineage: Campylobacter lari; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Causes gastrointestinal disease. This organism is closely related to C. jejuni and C. coli and is a foodborne pathogen that causes gastroenteritis and diarrhea. In addition this organism can cause bacteremia and septicemia in immunocompromised individuals. The bacterium is found in a variety of habitats including water environments, and seagulls are considered a reservoir for the organism. Shellfish can harbor the organism when inhabiting water contaminated by seagulls carrying the organism.