Pre_GI: SWBIT SVG BLASTP

Query: NC_014802:441000 Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, complete

Lineage: Campylobacter jejuni; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Gram-negative, microaerophilic, flagellate, spiral bacterium, Campylobacter species are the leading cause of food-borne gastroenteritis in developed countries. Infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome (GBS). Strain ICDCCJ07001 was isolated following a GBS outbreak in Shuangyang, a town in northern China in 2007, from a severely affected 15 year-old girl GBS patient who had been on a ventilator for 180 days. Her clinical symptoms were motor axonal neuropathy. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.

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BLASTP Alignment.txt

Subject: NC_011025:183287 Mycoplasma arthritidis 158L3-1, complete genome

Lineage: Mycoplasma arthritidis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: This organism causes arthritis in both rats and mice. Strains of Mycoplasma arthritidis can be virulent or avirulent depending, in part, on the presence of the MAV1 bacteriophage. This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucouse membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most of mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.