General Information: Gram-negative, microaerophilic, flagellate, spiral bacterium, Campylobacter species are the leading cause of food-borne gastroenteritis in developed countries. Infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome (GBS). Strain ICDCCJ07001 was isolated following a GBS outbreak in Shuangyang, a town in northern China in 2007, from a severely affected 15 year-old girl GBS patient who had been on a ventilator for 180 days. Her clinical symptoms were motor axonal neuropathy. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Gram-negative soil bacterium. This is the most widely studied species in the genus. Strains of Agrobacterium are classified in three biovars based on their utilisation of different carbohydrates and other biochemical tests. The differences between biovars are determined by genes on the single circle of chromosomal DNA. Biovar differences are not particularly relevant to the pathogenicity of A. tumefaciens, except in one respect: biovar 3 is found worldwide as the pathogen of gravevines. This species causes crown gall disease of a wide range of dicotyledonous (broad-leaved) plants, especially members of the rose family such as apple, pear, peach, cherry, almond, raspberry and roses. Because of the way that it infects other organisms, this bacterium has been used as a tool in plant breeding. Any desired genes, such as insecticidal toxin genes or herbicide-resistance genes, can be engineered into the bacterial DNA, and then inserted into the plant genome. This process shortens the conventional plant breeding process, and allows entirely new (non-plant) genes to be engineered into crops.