Query: NC_014761:743113 Oceanithermus profundus DSM 14977 chromosome, complete genome
Lineage: Oceanithermus profundus; Oceanithermus; Thermaceae; Thermales; Deinococcus-Thermus; Bacteria
General Information: Environment: Deep sea, Hydrothermal vent, Marine; Temp: Thermophile; Temp: 60C; Isolation:deep sea hot vent Pacific Ocean: East Pacific Rise. Oceanithermus profundus is a moderate thermophile originally isolated from a hydrothermal vent in the Pacific Ocean.
Subject: NC_009142:949510 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.