Query: NC_014657:1518721 Caldicellulosiruptor owensensis OL chromosome, complete genome Lineage: Caldicellulosiruptor owensensis; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Country: USA; Environment: Hot spring; Isolation: Freshwater sediment; Temp: Hyperthermophile; Temp: 79C; Isolation: freshwater sediment, Owens Lake, California. Caldicellulosiruptor owensensis is a thermphilic gram positive bacterium. This organism produces a thermostable xylanase which may have industrial uses.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.