Query: NC_014624:2668157 Eubacterium limosum KIST612 chromosome, complete genome Lineage: Eubacterium limosum; Eubacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria General Information: Eubacterium limosum KIST612 is an acetogenic bacterium isolated from an anaerobic digester and has a high growth rate on synthesis gas (CO; carbon monoxide) using it as a sole energy source. This organism produces acetate as well as butyrate and ethanol as fermentation products from syngas. Therefore, E. limosum KIST612 has been considered for a model strain for bioenergy production from syngas (obtained from biomass).
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General Information: This strain (UTI89) is a uropathogenic strain isolated from a woman with uncomplicated cystitis (bladder inflammation) that has been demonstrated to cause cystitis in a murine urinary tract infection model. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.