Query: NC_014623:6950638 Stigmatella aurantiaca DW4/3-1 chromosome, complete genome Lineage: Stigmatella aurantiaca; Stigmatella; Cystobacteraceae; Myxococcales; Proteobacteria; Bacteria General Information: Social gliding soil bacterium. Stigmatella aurantica, commonly isolated from rotting wood and bark, is a member of a group of organisms called myxobacteria. These organisms have a complex development and differentiation life cycle. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100,000 cells. Stigmatella aurantica produces a number of compounds, such as aurafuron A and stigmatellin, which may be important as anti-cancer agents.
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General Information: This symbiotic and thermophilic bacterium was discovered by screening for thermostable tryptanophases in Japanese compost. Cultured growth of this organism requires the presence of another bacterial species, such as a Bacillus or Escherichia coli, which provides diffusable metabolites required for its growth. Pure cultures can be obtained by growing Symbiobacterium thermophilum in a bioreactor, separated from its symbiotic counterpart by a dialysis membrane. Because of its symbiotic nature, it cannot be cultured with conventional methods. Despite a negative reaction for gram stain, this species is placed with the gram-positive bacteria based on 16s phylogenetic analysis.