Query: NC_014499:63365 Candidatus Sulcia muelleri CARI chromosome, complete genome Lineage: Sulcia muelleri; Sulcia; ; Flavobacteriales; Bacteroidetes; Bacteria General Information: This organism is a gut symbiont of the Blue-Green Sharpshooter and several other leafhopper species. It synthesizes amino acids for the host, enabling the leafhopper to live on a diet of plant sap. The Blue-Green Sharpshooter is an important vector for Pierce's Disease in plants, caused by the spread of Xylella fastidiosa.
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General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.