Query: NC_014484:447889 Spirochaeta thermophila DSM 6192 chromosome, complete genome Lineage: Spirochaeta thermophila; Spirochaeta; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria General Information: Strain DSM 6192 was isolated from brackish thermal Spring RI 19 on the edge of Green Lake on Raoul Island in the Kermadec archipelago about 1000 km northeast of New Zealand. Spirochaeta thermophila is a thermophilic obligately anaerobic spirochete. This organism has been isolated from brackish and marine hot springs.
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General Information: This organism is found in adult humans and formula fed infants as a normal component of gut flora. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity.