Query: NC_014328:1596016 Clostridium ljungdahlii ATCC 49587 chromosome, complete genome Lineage: Clostridium ljungdahlii; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: This strain was isolated from chicken yard waste and is studied for its ability to produce ethanol. This acetogenic species has the ability to convert carbon monoxide into ethanol. The yield of this process has been increased substantially in the laboratory by using a dual-fermentation system. A methanogenic conversion step has also been designed for utilizing some of the waste products generated during the synthetic process.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.