Query: NC_014215:1929000 Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Lineage: Propionibacterium freudenreichii; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Propionibacterium freudenreichii is a member of the "dairy propionibacteria", commonly isolated from cheese and other dairy products. Propionibacterium freudenreichii subsp. shermanii, formerly Propionibacterium shermanii, is important for the development of flavor and the characteristic holes in Swiss cheese. In addition, Propionibacterium freudenreichii subsp. shermanii has been used as a probiotic for humans and animals and may have a role in preventing of colon cancer.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.