Query: NC_014209:136152 Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome, Lineage: Thermoanaerobacter mathranii; Thermoanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Isolation: Hot spring; Country: Iceland; Temp: Thermophile; Temp: 70 - 75C; Habitat: Hot spring. A thermophilic bacterial species of straight rods, occurring singly or sometimes in long chains, motile and Gram variable. Isolated from hot spring, canned foods and dairy products.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.