Pre_GI: SWBIT SVG BLASTP

Query: NC_014169:1740243 Bifidobacterium longum subsp. longum JDM301 chromosome, complete

Lineage: Bifidobacterium longum; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is found in adult humans and formula fed infants as a normal component of gut flora.

Subject: NC_014623:5885903 Stigmatella aurantiaca DW4/3-1 chromosome, complete genome

Lineage: Stigmatella aurantiaca; Stigmatella; Cystobacteraceae; Myxococcales; Proteobacteria; Bacteria

General Information: Social gliding soil bacterium. Stigmatella aurantica, commonly isolated from rotting wood and bark, is a member of a group of organisms called myxobacteria. These organisms have a complex development and differentiation life cycle. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100,000 cells. Stigmatella aurantica produces a number of compounds, such as aurafuron A and stigmatellin, which may be important as anti-cancer agents.