Query: NC_014165:597000 Thermobispora bispora DSM 43833 chromosome, complete genome
Lineage: Thermobispora bispora; Thermobispora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Isolation: Decaying manure; Temp: Thermophile; Temp: 55 - 65C; Isolation: decaying manure. Thermobispora bispora is a thermophilic actinomycete which is able to grow at 65 degrees C and not at 35 degrees C. This organism forms aerial mycelia which contain longitudinal pairs of spores.
Subject: NC_010162:573709 Sorangium cellulosum 'So ce 56', complete genome
Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria
General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.