Query: NC_014160:43486 Thermosphaera aggregans DSM 11486 chromosome, complete genome Lineage: Thermosphaera aggregans; Thermosphaera; Desulfurococcaceae; Desulfurococcales; Crenarchaeota; Archaea General Information: Isolation: Hot spring from Obsidian Pool located in the Mud Volcano area of the Yellowstone National Park; Country: USA; Temp: Hyperthermophile; Temp: 85C; Habitat: Hot spring, Solfataric field. Thermosphaera aggregans is a hyperthermophilic archaeum isolated from terrestrial hot solfataric springs.
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General Information: This serovar has a narrow host range and causes a typhoid-like (paratyphoid fever) illness in humans. It is especially prevalent in southern and eastern Asia, and has been associated with some particularly virulent outbreaks. A number of isolates are increasingly antibiotic resistant. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.