Pre_GI: SWBIT SVG BLASTP

Query: NC_014150:2617072 Brachyspira murdochii DSM 12563 chromosome, complete genome

Lineage: Brachyspira murdochii; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Environment: Host, Intestinal microflora; Isolation: intestinal contents of healthy swine; Temp: Mesophile. Formerly Serpulina murdochii, this organism is part of the normal flora of the pig gastrointestinal tract.

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Subject: NC_012225:1213421 Brachyspira hyodysenteriae WA1, complete genome

Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.