Query: NC_014121:2629075 Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete Lineage: Enterobacter cloacae; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Enterobacter species are found in natural environments such as water, sewage, soil, and vegetables; some species are found in human and animal species. Enterobacter cloacae is a prevalent nosocomial pathogen as it is highly resistant to disinfectants and antimicrobial agents. E.cloacae subsp. cloacae strain ATCC 13047 was isolated from human cerebrospinal fluid in 1890 and is the type strain. These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment.
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General Information: This strain was isolated from sediment contaminated with cis-dichloroethane (cDCE), a common pollutant resulting from widespread manufacture and use of industrial solvents. This bacterium is the only known organism capable of using cDCE as a sole carbon and energy source. The ability of this strain to convert ethene to epoxyethane suggests that the first step in the cDCE biodegradation pathway is the oxidation of cDCE to an epoxide compound. Bacteria that are able to grow on cDCE are rare, and have only been found in very few highly selective artificial environments. The discovery of this bacteria may provide a low cost, self-sustaining bioremediation method in areas where cDCE is a problem contaminant.