Pre_GI: SWBIT SVG BLASTP

Query: NC_014107:171170 Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A,

Lineage: Enterobacter cloacae; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Enterobacter species are found in natural environments such as water, sewage, soil, and vegetables; some species are found in human and animal species. Enterobacter cloacae is a prevalent nosocomial pathogen as it is highly resistant to disinfectants and antimicrobial agents. E.cloacae subsp. cloacae strain ATCC 13047 was isolated from human cerebrospinal fluid in 1890 and is the type strain. These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment.

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BLASTP Alignment.txt

Subject: NC_009790:42112 Escherichia coli E24377A plasmid pETEC_74, complete sequence

Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: ETEC is the leading cause of traveler's diarrhea, characterized by a large volume of watery diarrhea. ETEC primarily colonizes the small intestine by way of the pili. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.