Pre_GI: SWBIT SVG BLASTP

Query: NC_014100:172452 Caulobacter segnis ATCC 21756 chromosome, complete genome

Lineage: Caulobacter segnis; Caulobacter; Caulobacteraceae; Caulobacterales; Proteobacteria; Bacteria

General Information: Isolation: Soil; Temp: Mesophile; Habitat: Fresh water. Caulobacter segnis strain ATCC 21756 is a prostheca-less bacterium belonging to the genus Caulobacter; it was isolated from soil although its habitat is considered to be fresh-water. The absence of a stalk in this genus makes this an interesting bacterium to study.

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Subject: NC_010673:703816 Borrelia hermsii DAH, complete genome

Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.