Query: NC_014041:4156059 Zunongwangia profunda SM-A87 chromosome, complete genome Lineage: Zunongwangia profunda; Zunongwangia; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria General Information: Zunongwangia profunda is an orange-pigmented, Gram-negative, nonmotile, strictly aerobic and oxidase- and catalase-positive bacterium isolated from the deep-sea sediment of the southern Okinawa Trough area.
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General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.