Pre_GI: SWBIT SVG BLASTP

Query: NC_014039:334892 Propionibacterium acnes SK137 chromosome, complete genome

Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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BLASTP Alignment.txt

Subject: NC_010002:5752363 Delftia acidovorans SPH-1, complete genome

Lineage: Delftia acidovorans; Delftia; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This species was isolated from soil enriched with acetamide in Delft in the Netherlands. It was originally classified as Comamonas acidivorans in 1926, and redescribed and characterized in 1999. This organism is found in soil, sediment, activated sludge, crude oil, water, and various clinical samples.