Pre_GI: SWBIT SVG BLASTP

Query: NC_014039:334892 Propionibacterium acnes SK137 chromosome, complete genome

Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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BLASTP Alignment.txt

Subject: NC_009654:1123709 Marinomonas sp. MWYL1, complete genome

Lineage: Marinomonas; Marinomonas; Oceanospirillaceae; Oceanospirillales; Proteobacteria; Bacteria

General Information: Marinomonas MWYL1 was isolated from the root surface of the salt marsh grass Spartina anglica, growing near the North Norfolk, England village of Stiffkey. The genus Marinomonas comprises a widespread group of g -proteobacteria that exist in coastal waters, and which had been earlier been included in the genus Alteromonas. The interest in Marinomonas MWYL 1 was that it could grow on the betaine molecule Dimethylsulphoniopropionate (DMSP) as sole carbon source and, when it did do, it released large amounts of the gas dimethyl sulphide. DMSP is a compatible solute that is used by many marine phytoplankton and seaweed macroalgae as an osmoticum and an anti-stress compound. In addition, a few known land angiosperms make DMSP and these include certain species of Spartina - hence the choice of these plants as a source for DMSP-degrading bacteria. Indeed, others had shown previously that the DMSP-catabolising bacteria isolated from Spartina root surfaces included Marinomonas strains.