Pre_GI: SWBIT SVG BLASTP

Query: NC_014039:334892 Propionibacterium acnes SK137 chromosome, complete genome

Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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BLASTP Alignment.txt

Subject: NC_007498:1148249 Pelobacter carbinolicus DSM 2380, complete genome

Lineage: Pelobacter carbinolicus; Pelobacter; Pelobacteraceae; Desulfuromonadales; Proteobacteria; Bacteria

General Information: Pelobacter carbinolicus DSM 2380 was isolated from mud in Venice, Italy. Iron- and sulfur-reducing bacterium. Pelobacter carbinolicus is commonly isolated from marine and freshwater sediments, and sewage sludge. This organism can make up a significant portion of the anaerobic microbial community in these environments. Pelobacter carbinolicus is also able to grow using iron and sulfur as terminal electron acceptors. This organism is closely related to the sulfur-reducing Desulfuromonas spp. and iron-reducing Geobacter spp..