Query: NC_014023:24000 Bacillus megaterium QM B1551 plasmid pBM700, complete sequence Lineage: Bacillus megaterium; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus megaterium is a naturally occurring soil bacterium, originally named because of its large size in relation to E. coli. This bacterium produces a number of useful enzymes, such as, amylases and proteases which have industrial uses. In addition this organism can be used for the production and export of other economically important compounds.
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General Information: This organism was one of the first bacteria studied, and was named Vibrio subtilis in 1835 and renamed Bacillus subtilis in 1872. It is one of the most well characterized bacterial organisms, and is a model system for cell differentiation and development. This soil bacterium can divide asymmetrically, producing an endospore that is resistant to environmental factors such as heat, acid, and salt, and which can persist in the environment for long periods of time. The endospore is formed at times of nutritional stress, allowing the organism to persist in the environment until conditions become favorable. Prior to the decision to produce the spore the bacterium might become motile, through the production of flagella, and also take up DNA from the environment through the competence system. The sporulation process is complex and involves the coordinated regulation of hundreds of genes in the genome. This initial step results in the coordinated asymmetric cellular division and endospore formation through multiple stages that produces a single spore from the mother cell.