Pre_GI: SWBIT SVG BLASTP

Query: NC_014013:112008 Sphingobium japonicum UT26S chromosome 2, complete genome

Lineage: Sphingobium japonicum; Sphingobium; Sphingomonadaceae; Sphingomonadales; Proteobacteria; Bacteria

General Information: Sphingobium japonicum (strain NBRC 101211 / UT26S) is a yellow-pigmented, non-motile, aerobic, hexachlorocyclohexane (HCH)-degrading Gram-negative bacterium isolated from a dumpsite in the vicinity of an industry that has been producing lindane. Sphingobium japonicum, formerly Sphingomonas paucimobilis, is able to degrade hexachlorocyclohexane which has been used extensively as insect control agents in the health and agriculture fields.

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Subject: NC_008011:1394777 Lawsonia intracellularis PHE/MN1-00, complete genome

Lineage: Lawsonia intracellularis; Lawsonia; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.