Query: NC_013967:1967896 Haloferax volcanii DS2 chromosome, complete genome
Lineage: Haloferax volcanii; Haloferax; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea
General Information: Haloferax volcanii DS2 was isolated from bottom sediments from the Dead Sea. Halophilic archaeon. This organism is similar to halobacteria and was originally classified in that genus. It has an optimum requirement for sodium chloride in the 1.7-2.5 molar which is half that generally associated with other halobacterium species.
Subject: NC_009142:949510 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.