Pre_GI: SWBIT SVG BLASTP

Query: NC_013949:939695 Helicobacter mustelae 12198 chromosome, complete genome

Lineage: Helicobacter mustelae; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Helicobacter mustelae was isolated from the gastric mucosa of a ferret. It is the natural colonizer of ferret gastric mucosa where it is found in association with a diffuse antral chronic gastritis and gastric ulcers. Inoculation of this bacteria into uninfected ferrets results in an inflammatory response similar to that seen in naturally infected animals, however, an association between gastric ulcers and Helicobacter mustelae infection has not yet been documented. All strains of this species have been reported to be urease, catalase and oxidase positive. Helicobacter mustelae is sensitive to 1.5% NaCl, metronidazole, and nalidixic acid and resistant to cephalothin and 5-fluorouracil.

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BLASTP Alignment.txt

Subject: NC_004545:141478 Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genome

Lineage: Buchnera aphidicola; Buchnera; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is found in the aphid Baizongia pistaciae. Aphid endosymbiont. It is believed that the Buchnera provide the essential nutrients the host lacks. Besides a nutritional co-dependence, due to a co-existence of millions of years, Buchnera have lost the ability to produce cell surface components such as lipopolysaccharides. This makes for an obligate endosymbiont relationship between host and Buchnera. Buchnera are prokaryotic cells which belong to the gamma-Proteobacteria, closely related to the Enterobacteriaceae family. Phylogenetic studies using 16S rRNA indicate that the symbiotic relationship was established around 200-250 million years ago. Since Buchnera are closely related to Escherichia coli and Haemophilus influenzae, comparative genomic studies can shed light on the evolutionary mechanisms of intracellular endosymbiosis as well as the different underlying molecular basis between organisms with parasitic behavior and symbionts.