Query: NC_013939:1767262 Deferribacter desulfuricans SSM1, complete genome Lineage: Deferribacter desulfuricans; Deferribacter; Deferribacteraceae; Deferribacterales; Deferribacteres; Bacteria General Information: Thermophilic sulphur-reducing bacterium. Isolated from a deep-sea hydrothermal vent chimney at the Suiyo Seamount in the Izu-Bonin Arc, Japan. Deferribacter desulfuricans is an anaerobic, heterotrophic thermophile. It is a strictly anaerobic heterotroph capable of using complex organic compounds, ethanol and various organic acids as energy and carbon sources. Elemental sulfur, nitrate or arsenate was required for growth as an electron acceptor.
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General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.