Query: NC_013889:413909 Thioalkalivibrio sp. K90mix chromosome, complete genome Lineage: Thioalkalivibrio; Thioalkalivibrio; Ectothiorhodospiraceae; Chromatiales; Proteobacteria; Bacteria General Information: Isolation: Highly alkaline soda lake sediment; Temp: Mesophile. Thioalkalivibrio sp. (strain K90mix) is an extremely salt tolerant (haloalkaliphilic), chemolithoautotrophic, sulfur-oxidizing Gram-negative bacterium isolated from a mixture of soda lake sediments.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.