Query: NC_013861:311908 Legionella longbeachae NSW150, complete genome Lineage: Legionella longbeachae; Legionella; Legionellaceae; Legionellales; Proteobacteria; Bacteria General Information: Legionella longbeachae is the predominant cause of Legionnaires' disease in Australia, but is an uncommon pathogen in other parts of the world. Legionella longbeachae infection has been associated with exposure to potting soil in Australia, the USA, Japan and the Netherlands. L. longbeachae is found predominantly in moist potting soil.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.