Query: NC_013798:345339 Streptococcus gallolyticus UCN34, complete genome Lineage: Streptococcus gallolyticus; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Isolated from a human case of endocarditis associated with colon cancer in Caen, France in 2001. Streptococci are non-motile, Gram-positive cocci with widely varying pathogenic potential that occur in pairs or chains. Streptococcus gallolyticus (strain UCN34, biotype I) is a commensal Gram-positive bacterium isolated from various habitats, including feces of many animals and from human clinical sources. S. gallolyticus is part of the rumen flora but also a cause of disease in ruminants as well as in birds (septicemia in pigeons, outbreaks in broiler flocks, or bovine mastitis). This is a tannin-degrading Streptococcus species. Strains have been isolated from various habitats, including feces of many animals and from human clinical sources. This organism can be a cause of infectious endocarditis.
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General Information: This strain (UTI89) is a uropathogenic strain isolated from a woman with uncomplicated cystitis (bladder inflammation) that has been demonstrated to cause cystitis in a murine urinary tract infection model. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.