Query: NC_013791:579842 Bacillus pseudofirmus OF4 chromosome, complete genome Lineage: Bacillus pseudofirmus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: This strain was isolated from soil in New York State by alkaline enrichment cultures. Because of its pH range and genetic accessibility, this alkaliphile has been extensively used as the model organism for studies of the bioenergetics of life at extremely high pH. This organism is a facultative, extreme alkaliphile that grows non-fermentatively as well as fermentatively in a pH range from near neutral to above pH 11.2.
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General Information: This bacterium, formerly Enterobacter sakazakii, is associated with infant septicemia, meningitis, and necrotizing enterocolitis. Originally isolated from powdered formula, it has also been shown to compartmentalize cerebral ventricles and cause brain abcesses in neonates. This species produces a yellow pigment when grown at 30 degrees C, but this fades at 37 degrees C.