Query: NC_013791:1152500 Bacillus pseudofirmus OF4 chromosome, complete genome
Lineage: Bacillus pseudofirmus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This strain was isolated from soil in New York State by alkaline enrichment cultures. Because of its pH range and genetic accessibility, this alkaliphile has been extensively used as the model organism for studies of the bioenergetics of life at extremely high pH. This organism is a facultative, extreme alkaliphile that grows non-fermentatively as well as fermentatively in a pH range from near neutral to above pH 11.2.
Subject: NC_012225:1901656 Brachyspira hyodysenteriae WA1, complete genome
Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.