Query: NC_013720:3925756 Pirellula staleyi DSM 6068, complete genome Lineage: Pirellula staleyi; Pirellula; Planctomycetaceae; Planctomycetales; Planctomycetes; Bacteria General Information: Isolation: Freshwater Lake Lansing, Michigan, USA; Temp: Mesophile; Temp: 20 - 25C; Habitat: Fresh water. Pirellula staleyi DSM 6068 is commonly isolated from freshwater environments. Pirellula staleyi is a pear-shaped bacterium having a life cycle consisting of an aggregate-forming sessile (non-motile) form and a motile swarmer cell. They have a pirellulosome, a large nucleoid-containing cellular compartment, which is surrounded by a single membrane.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.