Query: NC_013720:1605240 Pirellula staleyi DSM 6068, complete genome Lineage: Pirellula staleyi; Pirellula; Planctomycetaceae; Planctomycetales; Planctomycetes; Bacteria General Information: Isolation: Freshwater Lake Lansing, Michigan, USA; Temp: Mesophile; Temp: 20 - 25C; Habitat: Fresh water. Pirellula staleyi DSM 6068 is commonly isolated from freshwater environments. Pirellula staleyi is a pear-shaped bacterium having a life cycle consisting of an aggregate-forming sessile (non-motile) form and a motile swarmer cell. They have a pirellulosome, a large nucleoid-containing cellular compartment, which is surrounded by a single membrane.
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General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.