Query: NC_013716:4728500 Citrobacter rodentium ICC168, complete genome Lineage: Citrobacter rodentium; Citrobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.
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General Information: This strain (2CP-1; ATCC BAA-258) is the type strain for the species and was isolated from stream sediment near Lansing, Mich., USA. This anaerobic species was originally isolated by enrichment and isolation of single plate-grown colonies, and was the first pure culture of myxobacteria able to grow anaerobically. The unique physiological characteristics of this organism include the ability to use ortho-substituted mono- and dichlorinated phenols, nitrate, H2 and fumarate as terminal electron acceptors.