Query: NC_013716:4728500 Citrobacter rodentium ICC168, complete genome Lineage: Citrobacter rodentium; Citrobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.
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General Information: This organism was isolated from a calcereous (chalky) rock in Switzerland. Photosynthetic bacterium. This organism is an obligate photoautotroph that lacks thylakoid membranes and probably has its photosynthetic machinery in the cytoplasmic membrane with various components exposed to the periplasm whereas in other cyanobacteria the components are situated in the thylakoid membrane and are exposed to the cytoplasm. This unusual arrangement may be due to the lack of various fatty acids that are found in the thylakoid membrane in other cyanobacteria. It has been predicted that this organism was one of the earliest to diverge from the cyanobacterial line.