Query: NC_013716:2255102 Citrobacter rodentium ICC168, complete genome Lineage: Citrobacter rodentium; Citrobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.
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General Information: This organism was originally isolated from a rice field sample in Thailand. Burkholderia thailandensis is a common soil saprophyte (lives on decaying organic matter in the soil). This bacterium is very similar to the human and animal pathogen Burkholderia pseudomallei but appears to be avirulent. Distinguishing the two organisms is very difficult and may depend on using monoclonal antibodies to detect differences in exopolysaccharide production.