Query: NC_013716:2139952 Citrobacter rodentium ICC168, complete genome
Lineage: Citrobacter rodentium; Citrobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.
Subject: NC_014932:1232346 Bartonella clarridgeiae 73, complete genome
Lineage: Bartonella clarridgeiae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Bartonella clarridgeiae was first identified from a case of cat scratch fever in a veterinarian who had been bitten by a cat. This organism has subsequently been identified in both cats and dogs. Cats, which are infected by fleas carrying the bacteria, in turn infect humans when scratching or biting them, hence the name. A small red bump forms at the site of infection, followed 2-3 weeks later by a painful swelling of the lymph node. In immunocompromized patients, more severe progress may be observed, including encephalitis, swelling of the spleen, and heart valve infection. Approximately 24 000 cases are reported in the US each year.