Query: NC_013510:3640776 Thermomonospora curvata DSM 43183, complete genome Lineage: Thermomonospora curvata; Thermomonospora; Thermomonosporaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolation: Municipal refuse compost samples; Temp: Thermophile; Temp: 65C. An aerobic, cellulolytic, thermophilic Gram-positive bacterium isolated from straw compost. Thermomonospora curvata is a thermophilic bacterium which produces a number of industrially important compounds like cellulase, alpha-amylase, and polygalacturonate lyase.
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General Information: This organism has been implicated in a range of hypersensitivity pneumonitides, including farmer's lung disease. Symptoms of the disease develop in susceptible individuals following the inhalation of spores from overheated materials such as moldy hay and bagasse, or from forced-air heating and humidification systems. Prolonged exposure to the antigens results in acute respiratory distress which may lead to irreversible lung damage. Saccharomonospora viridis DSM 43017 was isolated from Irish peat and was originally classified as Thermomonospora viridis.