Query: NC_013416:668152 Aggregatibacter actinomycetemcomitans D11S-1, complete genome Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: Aggregatibacter actinomycetemcomitans D11S-1 was recovered from a subject with aggressive periodontitis. Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Pasteurella multocida subsp. multocida str. Pm70 was isolated in 1995 from a case of fowl cholera in chickens. Pathogen in humans, swine and poultry. This organism was one of the first pathogens ever sudied, and is named after Louis Pasteur, who used it in his vaccination studies in the 1880s. This organism usually resides in the mucous membranes of the intestinal, genital, and respiratory tissues and is an opportunistic pathogen that causes cholera in fowl, bovine hemorrhagic septicemia, and porcine atrophic rhinitis. Collectively these diseases cause millions of dollars in lost livestock every year. The organism can also infect humans if they are bitten by dogs and cats, which are carriers of the organism, but which are asymptomatic. This organism also expresses a hydrophilic capsule that inhibits phagocytosis and complemented-mediated attack.