Pre_GI: SWBIT SVG BLASTP

Query: NC_013416:1588369 Aggregatibacter actinomycetemcomitans D11S-1, complete genome

Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Aggregatibacter actinomycetemcomitans D11S-1 was recovered from a subject with aggressive periodontitis. Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.

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Subject: NC_009053:895965 Actinobacillus pleuropneumoniae L20, complete genome

Lineage: Actinobacillus pleuropneumoniae; Actinobacillus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This organism is an obligate parasite of pigs. The bacterium colonizes and invades the porcine lower respiratory tract and can survive phagocytosis by macrophages, eventually resulting in the death of the macrophage cell. Three RTS toxins, which result in cell damage, are produced by this organism.