Query: NC_013411:735838 Geobacillus sp. Y412MC61, complete genome Lineage: Geobacillus; Geobacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Isolation: Obsidian Hot Spring in Yellowstone; Country: USA; Temp: Mesophile. Recent rDNA analysis and DNA-DNA hybridization studies using spore-forming thermophilic subsurface isolates from formation waters of oilfields in Russia, Kazakhstan and China provided enough evidence to define the phylogenetically distinct, physiologically and morphologically consistent taxon Geobacillus. Geobacillus species are chemo-organotrophic, obligately thermophilic, neutrophilic, motile, spore-forming, aerobic or facultatively anaerobic.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.