Query: NC_013316:371953 Clostridium difficile R20291, complete genome Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.
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General Information: Environment: Fresh water; Temp: Mesophile. This is the first cultured species of the proposed new genus "Desulfurispirillum", and the sequencing of its genome will expand the range of experimental approaches that researchers can use to characterize its metabolic pathways for energy production and understand how these pathways are regulated. This organism is notable for its ability to reduce selenate to selenite and further to insoluble elemental selenium, in a process called dissimilatory selenate reduction.